GcMaf or Gc protein-derived macrophage activating factor is a protein by modification of vitamin D binding protein. GcMaf results from sequential deglycosylation (The removal of the sugar entity from glycogen, a substance deposited in bodily tissues as a store of carbohydrates.) of the vitamin D binding protein. It is naturally promoted by the lymphocytes (a type of white blood cell), B and T cells. The resulting protein may be a macrophage activating factor (MAF). MAFs are lymphokines (a substance created by lymphocytes that activates the immune system)

Fake Cure-All

The UK Medicines Healthcare Products Regulatory Agency and Cancer Research UK warned the public about the claims of clinical benefits. The appearance of a clinical benefit was based on the reduced levels of alpha-N-acetylgaloctosamindase enzyme (nagalase which is a liver enzyme). Many cancers cause an overproduction of nagalase.

Autistic children being dosed with GcMaf were not exibiting autistic behaviors because they were suffering from horrible side effects. GcMaf is injected in the muscle or intramuscular injection.

Promotors of this dangerous substance were people such as Amanda Mary Jewell and Jeff Bradstreet. 

Side effects:

Toxic shock
headaches
nausea
abdominal pain

Sources

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(Retracted) Yamamoto, Nobuto; Ushijima, Naofumi; Koga, Yoshihiko (January 2009). “Immunotherapy of HIV-infected patients with Gc protein-derived macrophage activating factor (GcMAF)”. Journal of Medical Virology. 81 (1): 16–26. doi:10.1002/jmv.21376. PMID 19031451.
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(Retracted) Yamamoto, Nobuto; Suyama, Hirofumi; Yamamoto, Nobuyuki; Ushijima, Naofumi (15 January 2008). “Immunotherapy of metastatic breast cancer patients with vitamin D-binding protein-derived macrophage activating factor (GcMAF)”. International Journal of Cancer. 122 (2): 461–467. doi:10.1002/ijc.23107. PMID 17935130.
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